This lecture is not intended for those who are accustomed to hear discourses which inquire more deeply into the human constitution than is profitable for medical stduy. I am not going to assert that man is all air, or fire, or water, or earth; or infact anything but what manifestly composes his body; let those who like discuss such matters...They all, theorizing, draw the same deduction, asserting that there is one basic substance which is unique and the basis of everything; but they call it by different names, one insisting that it is air, another that it is fire, another water, another earth...Thus they serve, rather, to establish the theory of Melissus.
Hippocratic Writings page 260