Statistics for occurrence #1 of “the Appalachians” in chapter 1 of Maj. Jed. Hotchkiss, Confederate Military History, a library of Confederate States Military History: Volume 3, Virginia:

...on in Virginia with the great prairie States. The Baltimore & Ohio railroad had but just opened communication by rail with that region. None other of the railways of Virginia had then crossed the Appalachians , consequently there was none of that destructive competition which has now made farming unprofitable in the Atlantic States. The wheat from Virginia, much of it ground into flour by local mills, es...
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