Statistics for occurrence #1 of “Upper Mississippi” in article 1 of The Daily Dispatch: may 18, 1861., [Electronic resource]:

... with both belligerents. "Fortunately, it is not too late to put one question to the Government, and to take steps for the protection of whatever cotton may be at this moment in transitu by the Upper Mississippi and the lakes. There is reason to believe that hereafter American armed vessels on the Ohio river will intercept all further shipments by that route; but it is highly probable that large quantities...

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