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[195] whose sunlight fades not from memory, were passed at Wormsloe, on the Isle of Hope, the abode of his ancestors. There in infancy were his loves of Georgia begotten. There was his knowledge of home and country localized. There were attachments born which remained ever part and parcel of his inner being.

When not yet twelve years old, upon the death of his father, he accompanied his mother to Philadelphia. There he pursued his academic studies, and was, in due course, admitted as a member of the Collegiate Department of the University of Pennsylvania. His proficiency in the acquisition of knowledge, and his intellectual capabilities attracted the notice and evoked the commendation of his teachers. It was natural that he should seek an education in that city and from that institution, for both were allied to him by ties of no ordinary significance. His maternal grandfather, Justice Thomas Smith, had been for many years a prominent lawyer and a distinguished judge in Philadelphia, and his maternal great uncle, the Reverend William Smith, D. D., was the first provost of the institution now known as the University of Pennsylvania. He was a noted teacher, an accomplished writer, and an eloquent divine. A native of Scotland and a graduate of the University of Aberdeen, shortly after his removal to America, he identified himself with all that was progressive and of high repute in the City of Brotherly Love. After a long life spent in rendering important service to the literary, educational, and religious interests of this country, he died in the city of his adoption on the 14th of May, 1803. His scholarly works and the institution he founded are living monuments to his memory.

In his maternal home, and upon the benches whence had gone forth many who had been instructed by his distinguished relative, Mr. DeRenne found opportunity for earnest study. Graduating with honor, and selecting medicine as the profession best suited to his tastes, he became a private pupil of the famous Dr. Samuel Jackson, and entered the Medical School of the University of Pennsylvania. This college was, at that time, probably the most noted in the United States, and the facilities there afforded for mastering the mysteries of the Healing Art were unsurpassed this side the Atlantic. Mr. De-Renne's graduating thesis was entitled a ‘Theory concerning the Nature of Insanity.’ In was, in 1847, privately printed, to the number of forty-eight copies, for special distribution. Striking in thought and composition is this production, indicating an amount of careful research, delicate analysis, and philosophical deduction quite uncommon in one who had barely attained unto his majority. It elicited

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