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careful: out of 25 instances, four, or at most five, have the sense ‘full of care or anxiety’ Err. V. i. 299, R2 II. ii. 75 “careful business,” H5 IV. i. 251 “our careful wives,” R3 I. iii. 83 “him that rais'd me to this careful height” ; Tw.N. IV. ii. 11 “a careful man” (? =careworn from much study).