Statistics for occurrence #1 of “Dr. Holmes” in chapter 6 of Lucius R. Paige, History of Cambridge, Massachusetts, 1630-1877, with a genealogical register:

... Dr. Holmes
Prosperity of the New Town. magistrates. Courts. dissatisfaction. John Pratt. straitness for want of land. Explorati...
Max. Freq. Min. Freq.
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† This entity has been selected by the automated classifier as the most likely match in this context. It may or may not be the correct match.