Statistics for occurrence #1 of “Dr. Hedge” in chapter 14 of Jula Ward Howe, Reminiscences: 1819-1899:

...once gave a party and invited only friends from Boston, leaving out all her Cambridge acquaintances, who, in consequence, were much offended, and ceased to make their usual calls. A sister of his, Dr. Hedge said, was the only one of those ladies who continued to visit her. He saw Margaret for the last time in Rome, and found her much changed and subdued. She was laboring at the time under one of t...
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