A.to be in a bad state, Hp.Coac.194; πονηρευόμενα ἕλκη malignant ulcers, Dsc.1.106, cf. Ruf. ap. Orib.45.30.31.
II. act wickedly, play the knave, Heraclit.125a, Arist.Rh.1411a17, Men. Epit.133; “οἱ πεπονηρευμένοι” D.19.32, cf. Phld.Rh.1.43 S., Plu.Cat.Ma. 9, etc.: c. dat., towards or against . . , Thd.Su.61: with Preps., “ἐν τοῖς προφήταις” LXX 1 Ch.16.22; “κατ᾽ ἐμοῦ” Thd.Su.43: also c. acc., τινα LXX Ec.7.22(23); intend maliciously, c. inf., ib.De.19.19; τοῦ ἀποκτεῖναί τινα ib.Ge.37.18, al.