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That same year Nero was believed to have destroyed by poison two of his most powerful freedmen, Doryphorus, on the pretext of his having opposed the marriage with Poppæa, Pallas for still keeping his boundless wealth by a prolonged old age. Romanus had accused Seneca in stealthy calumnies, of having been an accomplice of Caius Piso, but he was himself crushed more effectually by Seneca on the same charge. This alarmed Piso, and gave rise to a huge fabric of unsuccessful conspiracies against Nero.