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8. Therefore, if all this is as we have explained, our reason showing us that the bodies of animals are made up of the elements, and these bodies, as we believe, giving way and breaking up as a result of excess or deficiency in this or that element, we cannot but believe that we must take great care to select a very temperate climate for the site of our city, since healthfulness is, as we have said, the first requisite.
Vitruvius: The Ten Books on Architecture. Vitruvius. Morris Hicky Morgan. Cambridge: Harvard University Press. London: Humphrey Milford. Oxford University Press. 1914.
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